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        Nc2Eye

           A curated ncRNAomics knowledgebase for bridging basic and clinical research in eye diseases.

Detail of Behcet's disease (BD)
ncRNA name hsa-miR-196a2
ncRNA Category miRNA
Disease name Behcet's disease (BD)
Species Homo sapiens
Tissues/Cell_line peripheral blood mononuclear cells (PBMCs)
Methods PCR-RFLP, qPCR, CCK-8 assay, ELISA
Expression pattern associated
Functional description This study shows that a functional variant of miR-196a2 confers risk for BD but not for VKH syndrome or AAU(+)AS(+) by modulating the miR-196a gene expression and by regulating pro-inflammatory IL-1β and MCP-1 production.
PubMed ID 23928854
Year 2013
Title A functional variant of pre-miRNA-196a2 confers risk for Behcet's disease but not for Vogt-Koyanagi-Harada syndrome or AAU in ankylosing spondylitis.
Drug-related ncRNA NO

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