ncRNA name | hsa-miR-196a2 |
ncRNA Category | miRNA |
Disease name | Behcet's disease (BD) |
Species | Homo sapiens |
Tissues/Cell_line | peripheral blood mononuclear cells (PBMCs) |
Methods | PCR-RFLP, qPCR, CCK-8 assay, ELISA |
Expression pattern | associated |
Functional description | This study shows that a functional variant of miR-196a2 confers risk for BD but not for VKH syndrome or AAU(+)AS(+) by modulating the miR-196a gene expression and by regulating pro-inflammatory IL-1β and MCP-1 production. |
PubMed ID | 23928854 |
Year | 2013 |
Title | A functional variant of pre-miRNA-196a2 confers risk for Behcet's disease but not for Vogt-Koyanagi-Harada syndrome or AAU in ankylosing spondylitis. |
Drug-related ncRNA | NO |
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